Nguyen Van Thanh, Nguyen Hai Dang, Phan Van Kiem, Nguyen Xuan Cuong, Hoang Thanh Huong, Chau Van Minh

Bioassay guided fractionation led to the isolation of a new triterpene glycoside, holothurinogenin B (1) along with three known compounds, holothurin B (2), holothurin A (3), and holothurin A₂ (4), from the methanol extract of the Vietnamese sea cucumber Holothuria scabra. Their structures were deduced from the spectral analysis (1D-NMR, 2D-NMR, MS) and chemical evidences.

Keywords: Triterpene glycosides, Sea cucumber, Holothuria scabra, Holothurinogenin B.

AJSTD Vol. 23 Issue 4 pp. 253-260 (2006)